A Tool to Change Human Antigen R Protein Expression: May Have Implications in both Cancer & Diabetes >


Copyright © 2014 by Dr. Kerry Masterson  ·  All Rights reserved  ·  E-Mail: km@humanantigenr.com

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Human Antigen R mRNA Protective Sequence Site
PubMed search HuR AND Lung Cancer

1: Yang Z, Zheng R, Gao Y, Zhang Q. Gene expression profiles on predicting protein interaction network and exploring of new treatments for lung cancer. Mol Biol Rep. 2014 Sep 10. [Epub ahead of print] PubMed PMID: 25205123.

2: Li YJ, Wang CH, Zhou Y, Liao ZY, Zhu SF, Hu Y, Chen C, Luo JM, Wen ZK, Xu L.TLR9 signaling repressed tumor suppressor miR-7 expression through up-regulation of HuR in human lung cancer cells. Cancer Cell Int. 2013 Sep 3;13(1):90. doi:10.1186/1475-2867-13-90. PubMed PMID: 24004462; PubMed Central PMCID: PMC3847485.

3: Lauriola L, Serini S, Granone P, Lanza P, Martini M, Calviello G, Ranelletti FO. Hu/elav RNA-binding protein HuR regulates parathyroid hormone related peptide expression in human lung adenocarcinoma cells. Histol Histopathol. 2013Sep;28(9):1205-16. Epub 2013 Apr 10. PubMed PMID: 23572284.

4: Hsia TC, Tu CY, Chen YJ, Wei YL, Yu MC, Hsu SC, Tsai SL, Chen WS, Yeh MH, Yen CJ, Yu YL, Huang TC, Huang CY, Hung MC, Huang WC. Lapatinib-mediated cyclooxygenase-2 expression via epidermal growth factor receptor/HuR interaction
enhances the aggressiveness of triple-negative breast cancer cells. Mol Pharmacol. 2013 Apr;83(4):857-69. doi: 10.1124/mol.112.082743. Epub 2013 Jan 25. PubMed PMID: 23355539.

5: Sun L, Zhang S, Jiang Z, Huang X, Wang T, Huang X, Li H, Zhang L. Triptolide inhibits COX-2 expression by regulating mRNA stability in TNF-α-treated A549 cells. Biochem Biophys Res Commun. 2011 Dec 9;416(1-2):99-105. doi:
10.1016/j.bbrc.2011.11.004. Epub 2011 Nov 10. PubMed PMID: 22093832.

6: Liao WL, Wang WC, Chang WC, Tseng JT. The RNA-binding protein HuR stabilizes cytosolic phospholipase A2α mRNA under interleukin-1β treatment in non-small cell lung cancer A549 Cells. J Biol Chem. 2011 Oct 14;286(41):35499-508. doi:
10.1074/jbc.M111.263582. Epub 2011 Aug 23. PubMed PMID: 21862584; PubMed Central PMCID: PMC3195591.

7: Wang J, Wang B, Bi J, Zhang C. Cytoplasmic HuR expression correlates with angiogenesis, lymphangiogenesis, and poor outcome in lung cancer. Med Oncol. 2011Dec;28 Suppl 1:S577-85. doi: 10.1007/s12032-010-9734-6. Epub 2010 Nov 3. PubMed PMID: 21046284.

8: Xiao J, Tan Y, Pan Y, Liang G, Qu C, Zhang X, Zhang Y, Li X, Yang H. A new cyclooxygenase-2 inhibitor, (1E,4E)-1,5-bis(2-bromophenyl)penta-1,4-dien-3-one (GL63) suppresses cyclooxygenase-2 gene expression in human lung epithelial
cancer cells: coupled mRNA stabilization and posttranscriptional inhibition. Biol Pharm Bull. 2010;33(7):1170-5. PubMed PMID: 20606309.

9: Abdelmohsen K, Kim MM, Srikantan S, Mercken EM, Brennan SE, Wilson GM, Cabo Rd, Gorospe M. miR-519 suppresses tumor growth by reducing HuR levels. Cell Cycle. 2010 Apr 1;9(7):1354-9. Epub 2010 Apr 1. PubMed PMID: 20305372; PubMed Central PMCID: PMC3057889.

10: Lim SJ, Lee SH, Joo SH, Song JY, Choi SI. Cytoplasmic expression of HuR is related to cyclooxygenase-2 expression in colon cancer. Cancer Res Treat.  Jun;41(2):87-92. doi: 10.4143/crt.2009.41.2.87. Epub 2009 Jun 30. PubMed PMID:
19707506; PubMed Central PMCID: PMC2731207.

11: Strimpakos AS, Syrigos KN, Saif MW. Pharmacogenetics in pancreatic cancer. Highlights from the 45th ASCO annual meeting. Orlando, FL, USA. May 29-June 2, 2009. JOP. 2009 Jul 6;10(4):357-60. PubMed PMID: 19581734.

12: Wang J, Zhao W, Guo Y, Zhang B, Xie Q, Xiang D, Gao J, Wang B, Chen Z. The expression of RNA-binding protein HuR in non-small cell lung cancer correlates with vascular endothelial growth factor-C expression and lymph node metastasis.
Oncology. 2009;76(6):420-9. doi: 10.1159/000216837. Epub 2009 May 5. PubMed PMID: 19420963.

13: Wang J, Guo Y, Zhang B, Chen Z, Gao J, Zhao Y, Xiang D. [The expression of human antigen R and vascular endothelial growth factor-C and their significance in non-small cell lung cancer]. Zhongguo Fei Ai Za Zhi. 2007 Dec 20;10(6):481-5.
doi: 10.3779/j.issn.1009-3419.2007.06.07. Chinese. PubMed PMID: 21129304.

14: López de Silanes I, Lal A, Gorospe M. HuR: post-transcriptional paths tomalignancy. RNA Biol. 2005 Jan;2(1):11-3. Epub 2005 Jan 19. PubMed PMID:17132932.