A Tool to Change Human Antigen R Protein Expression: May Have Implications in both Cancer & Diabetes >

 

Copyright © 2014 by Dr. Kerry Masterson  ·  All Rights reserved  ·  E-Mail: km@humanantigenr.com
 
 

  HuR: A Cancer and Diabetes Target          HuR mRNA Protective Sequence (HPS)           HPS Experiment Results          Contact
Human Antigen R mRNA Protective Sequence Site
 
PubMed search HuR AND Leukemia


1: Podszywalow-Bartnicka P, Wolczyk M, Kusio-Kobialka M, Wolanin K, Skowronek K, Nieborowska-Skorska M, Dasgupta Y, Skorski T, Piwocka K. Downregulation of BRCA1 protein in BCR-ABL1 leukemia cells depends on stress-triggered TIAR-mediatedsuppression of translation. Cell Cycle. 2014 Sep 19:0. PubMed PMID: 25483082.

2: Baou M, Norton JD, Murphy JJ. AU-rich RNA binding proteins in hematopoiesis and leukemogenesis. Blood. 2011 Nov 24;118(22):5732-40. doi:10.1182/blood-2011-07-347237. Epub 2011 Sep 13. PubMed PMID: 21917750.

3: Siddiqui N, Borden KL. mRNA export and cancer. Wiley Interdiscip Rev RNA. 2012 Jan-Feb;3(1):13-25. doi: 10.1002/wrna.101. Epub 2011 Jul 27. Review. PubMed PMID: 21796793.


4: Ishimaru D, Ramalingam S, Sengupta TK, Bandyopadhyay S, Dellis S, Tholanikunnel BG, Fernandes DJ, Spicer EK. Regulation of Bcl-2 expression by HuR in HL60 leukemia cells and A431 carcinoma cells. Mol Cancer Res. 2009
Aug;7(8):1354-66. doi: 10.1158/1541-7786.MCR-08-0476. Epub 2009 Aug 11. PubMed PMID: 19671677.


5: Sobue S, Murakami M, Banno Y, Ito H, Kimura A, Gao S, Furuhata A, Takagi A, Kojima T, Suzuki M, Nozawa Y, Murate T. v-Src oncogene product increases sphingosine kinase 1 expression through mRNA stabilization: alteration of AU-rich
element-binding proteins. Oncogene. 2008 Oct 9;27(46):6023-33. doi: 10.1038/onc.2008.198. Epub 2008 Jun 23.
PubMed PMID: 18574469.

6: Annabi B, Currie JC, Moghrabi A, Béliveau R. Inhibition of HuR and MMP-9 expression in macrophage-differentiated HL-60 myeloid leukemia cells by green tea polyphenol EGCg. Leuk Res. 2007 Sep;31(9):1277-84. Epub 2006 Nov 1. PubMed PMID: 17081606.


7: Champelovier P, Pautre V, Elatifi M, Dupré I, Rostaing B, Michoud A, Berger F, Seigneurin D. Resistance to phorbol ester-induced differentiation in human myeloid leukemia cells: a hypothetic role for the mRNA stabilization process. Leuk Res. 2006 Nov;30(11):1407-16. Epub 2006 Jun 6. PubMed PMID: 16757024.


8: Li Y, Jiang ZZ, Chen HX, Leung WK, Sung JJ, Ma WJ. The existence of a putative regulatory element in 3'-untranslated region of proto-oncogene HOX11's mRNA. J Biochem Mol Biol. 2005 Jul 31;38(4):500-6. PubMed PMID: 16053719.